Products
Redefine Beauty
with Science
From dermal fillers to skin boosters, our range unites innovation, safety, and comfort to deliver natural, lasting results tailored to every face.
Saypha® Dermal Filler Range
HA Concentration
23-25 mg/mL
Lidocaine
0.3%
Crosslinker
BDDE (≤2 ppm)
Syringe
1.0 mL prefilled
Duration
Up to 13 months

Filling with comfort
saypha® filler lidocaine
Saypha Filler Lidocaine is a cross-linked hyaluronic acid dermal filler indicated to correct light to moderate nasolabial folds.
93% patient satisfaction at 36 weeks9
Smooth, homogeneous gel for natural correction
Injection into the mid to deep dermis for correction of light to moderate nasolabial folds
- Indication
- Light to moderate nasolabial folds
- HA Concentration
- 23 mg/mL
- Needle Gauge
- 2 × 27G × ½″ thin wall Terumo™ needles
- Duration
- Up to 9 months
- Lidocaine
- 0.3%
- Crosslinker
- BDDE (≤2 ppm)

Volumizing with comfort
saypha® volume lidocaine
Saypha Volume Lidocaine is a cross-linked hyaluronic acid dermal filler indicated to correct deeper wrinkles in nasolabial folds.
93.5% patient satisfaction rate and aesthetic improvement17
Designed for application with needle or cannula
Injection into the deep dermis for correction of deeper nasolabial folds
- Indication
- Deep wrinkles in nasolabial folds
- HA Concentration
- 23 mg/mL
- Needle Gauge
- 2 × 27G × ½″ thin wall Terumo™ needles
- Duration
- Up to 9 months
- Lidocaine
- 0.3%
- Crosslinker
- BDDE (≤2 ppm)

Contouring with precision
saypha® volume plus lidocaine
Saypha® volume plus Lidocaine is a cross-linked hyaluronic acid dermal filler indicated to correct moderate to severe midface volume deficit in the zygomaticomalar region, anteromedial cheek region and submalar region.
- Indication
- Moderate to severe midface volume deficit
- HA Concentration
- 25 mg/mL
- Needle Gauge
- 2 × 27G × ½″ thin wall Terumo™ needles
- Duration
- Up to 13 months
- Lidocaine
- 0.3%
- Crosslinker
- BDDE (≤2 ppm)
Skin Boosters
Revitalize from
within
Beyond filling and volumizing, skin boosters work at the superficial dermal level to improve hydration, elasticity, and overall skin quality — for a radiant, youthful complexion from the inside out.

Revitalizing with science
croma revitalis
Hyaluronic Mesotherapy
Croma revitalis is a non-crosslinked hyaluronic acid skin booster designed to improve skin hydration, elasticity, tone, and overall texture through superficial dermal injections. Formulated with glycerol for enhanced skin revitalization.
93% satisfaction rate at 9 months
97% of subjects demonstrated improvements at 9 months
Injection into the superficial dermal tissue to improve skin hydration and revitalization
- Indication
- Skin hydration & elasticity improvement
- HA Concentration
- 18 mg/mL
- Needle Gauge
- 1 × 30G ½″ thin wall Terumo™ needles
- Duration
- Up to 6 months
- Glycerol
- 21 mg/mL
Treatment Areas
Targeted Precision
Explore where each Saypha® product is indicated. Select a zone to learn more.

Experience your benefits
Your benefits with saypha®
By re-establishing your natural HA level, HA fillers can help to reverse the signs of aging.2,3 HA fillers can also be used to add volume7 and smooth out wrinkles where needed.
Fully satisfied patients1
90% of patients were satisfied with the treatment results even at month 9 after the treatment.a,1
Long term visible results9–19
After one year, 8 out of 10 participants still demonstrated aesthetic improvement.b,1
Natural-looking results
Formulated with hyaluronic acid, a naturally occurring substance in the skin, for results that enhance your natural beauty without looking overdone.2,3
Comfortable treatment
Incorporated lidocaine provides a numbing effect, supporting your comfort during the treatment.c,16
a Applies to VOLUME PLUS, as shown in the PRIMAvera clinical study. b Applies to VOLUME PLUS, based on clinical study data. c Lidocaine is incorporated in all saypha® Lidocaine products.